Thin film preparation is an important process in various scientific research and industrial applications, such as electronics, optics, and surface science. The quality of the thin film greatly depends on the substrate material, especially the charge status of the surface. In recent years, positive charged glass slides have gained increasing attention as a promising substrate for thin film preparation. In this article, we will discuss the advantages of positive charged glass slides over conventional glass slides for thin film preparation.

Firstly, positive charged glass slides have a higher affinity for negatively charged molecule or nanoparticle such as DNA, proteins, and nanoparticles than conventional glass slides. The surface of positive charged glass slide is covered with a layer of positive charge, which attracts and immobilizes negatively charged molecules or nanoparticles through electrostatic interaction. This can enhance the binding efficiency and reduce nonspecific adsorption, resulting in more uniform and reproducible thin films.

Secondly, positive charged glass slides have better wettability and adhesion properties than conventional glass slides. The hydrophilic property of the charged surface improves the contact angle between the substrate and solution, thus facilitating the uniform spreading of the solution on the substrate. Furthermore, the positively charged surface can promote the adhesion of the thin film to the substrate and prevent its delamination, which is critical for the stability and functionality of the thin film.

Thirdly, positive charged glass slides provide a wider range of applications in the preparation of thin films. The charged surface can be modified with various functional groups, such as amino, carboxyl, and sulfhydryl groups, through simple chemical reactions. These functionalized glass slides can selectively immobilize molecules or nanoparticles with specific chemical properties, such as aptamers, antibodies, and enzymes, and enable the fabrication of complex thin film structures.

In addition, positive charged glass slides are compatible with various analytical techniques, such as fluorescence microscopy, surface plasmon resonance, and quartz crystal microbalance, for real-time monitoring and characterization of the thin film formation process. The transparent nature of the glass substrate allows for direct observation and imaging of the thin film in situ, providing valuable insights into the underlying mechanisms and optimizing the fabrication parameters.

In summary, positive charged glass slides offer multiple advantages for thin film preparation, including improved binding efficiency, better wettability and adhesion, wider applications, and compatibility with various analytical techniques. These features make positive charged glass slides a promising substrate material for the development of high-quality and functional thin films in various scientific and industrial fields.

Reference

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2.Leonardo R. Allain, Karn Sorasaenee, and Ziling Xue.Doped Thin-Film Sensors via a Sol−Gel Process for High-Acidity Determination.ACS Nano 2011, 5, 11, 8552–8561.https://doi.org/10.1021/nn2029617